BDBM18355 (2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol::CHEMBL1029::MIGLUSTAT::N-Butyl-DNJ::US20230339856, Compound NB-DNJ::US9181184, 5
SMILES CCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO
InChI Key InChIKey=UQRORFVVSGFNRO-UTINFBMNSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 18355
Affinity DataIC50: 230nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of conduritol beta-epoxide-sensitive mouse glucosylceramidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of human GBA2More data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of GBA2 by HPLCMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of recombinant GBA2 preincuabated with compound for 30 mins using 4-methylumbelliferyl-B-glucoside substrate by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of non-lysosomal glucosylceramidase in cultured melanoma cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of glucosylceramidase 2 from spleen of patient with gaucher's disease by fluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair